Multicentric primary malignant melanomas of the choroid: two separate malignant melanomas of the choroid and two uveal naevi in one eye.
نویسندگان
چکیده
Two completely separate malignant melanomas of the choroid occurred in 1 eye containing 2 additional uveal naevi. Review of the literature disclosed 7 further patients with unilateral multicentric malignant melanomas of the choroid and 11 bilateral multicentric malignant melanomas of the uvea. General aspects of multicentric primary neoplasia are discussed and an interpretation is attempted.
منابع مشابه
Multiple malignant melanomata of the uveal tract in one eye.
THE literature on malignant melanoma of the uveal tract is extensive but case reports of multiple malignant tumours of this type are infrequent. Freckles and naevi are present in approximately 50 per cent. of normal eyes and "are even more frequent and larger in eyes which also contain malignant melanoma of the uveal tract" (Hogan and Zimmerman, 1962). According to Reese (1956), when the malign...
متن کاملDemonstration of biogenic amines and adrenergic innervation in uveal malignant melanomas by the histoflurometric method.
Clinical and histologic studies were performed on 25 patients with malignant melanomas of the ciliary body and choroid. Portions of fresh tumor were quick frozen and processed by the histofluorometric technique to demonstrate the presence of biogenic amines. Separate portions of each tumor were fixed and processed for routine light microscopy. Specific fluorescence was visible in 21 of 23 pigme...
متن کاملIncidence of ocular melanoma in the general population and in glaucoma patients.
Intraocular melanomas are the most common primary ocular malignancy in white people accounting for approximately 70% of all eye malignancies in adults. Most ocular melanomas arise from uveal melanocytes distributed throughout the stroma of the choroid, only 4%–10% of uveal melanomas originate in the iris. Data on the incidence of intraocular melanoma are limited with estimates of incidence rate...
متن کاملInternal resection of posterior uveal melanomas.
AIMS To evaluate the safety and efficacy of internal resection in the treatment of malignant melanoma of the choroid. METHODS 32 consecutive patients with histopathologically proved malignant choroidal melanomas were treated with internal resection. 29 of the 32 (90.6%) tumours were within 2 disc diameters of the optic nerve or fovea. The surgery was performed at two university centres by one...
متن کاملDoes enucleation of the eye containing a malignant melanoma prevent or accelerate the dissemination of tumour cells.
A reappraisal of survival data on patients with uveal melanomas has led us to these impressions: (a) that the mortality rate before enucleation is low, estimated at 1% per year; (b) that the mortality rate rises abruptly following enucleation, reaching a peak of about 8% during the second year after enucleation; and (c) that approximately two-thirds of the fatalities could be attributed to the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The British journal of ophthalmology
دوره 62 6 شماره
صفحات -
تاریخ انتشار 1978